International Genetically Engineered Machine (iGEM) 2019 was held on November 4, 2018 oflocal time in Boston. The representative team of Central South University CSU-CHINA composed of 20 undergraduates won the golden award. This is just the second time for the CSU undergraduates to form team and participated in iGEM. In CSU’s first show up at iGEM in 2018, its representative team won the silver award.
iGEM, as an international multidisciplinary and authoritative academic contest with core of synthetic biology, involves biology, computer science and mathematics. With wide international effect, it aims to encourage students to innovate actively for a better world. This year, near 400 teams from over 70 countries and regions took part in iGEM 2019, including representative teams from world-renown universities such as Massachusetts Institute of Technology, Harvard University, Yale University, University of Oxford and Stanford University, as well as domestic teams from Chinese famous universities like Peking University, Tsinghua University, University of Science and Technology of China, and Zhejiang University.
2019 CSU-CHINA relies on the scientific research platform of Medical Genetics Research Center, School of Life Sciences, and has academic advisors including Li Shanni, Li Jiada and Zeng Weiqian, and team members from School of Life Sciences, Xiang Ya School of Medicine and Xiang Ya Nursing School of CSU, with a captain Dong Yufan, a 2016’undergraduate from School of Life Sciences of CSU.
The project of 2019 CSU-CHINA is, for the targeted therapy against Triple Negative Breast Cancer (TNBC), to establish an artificial genetic logic loop in mammal cells through synthetic biology to developa therapy with specific lysis for TNBC cells. This loop comprehensively utilizes genetic elements such as promoter, miRNA and cRNA, effectively improves the specificity of drug therapy, reduces toxic and side effects in traditional cancer therapeutic process and provides a new train of thought for targeted therapy for TNBC. This project has won wide applause from the jury in oral report and wall newspaper demonstration.
The 2019 CSU-CHINA has obtained strong support from CSU’s Undergraduate School and School of Life Science as well as the support and guidance from Doctor Ming-Ru Wu from Massachusetts Institute of Technology, U.S.A.
Source: School of Life Science